XE-BIO - Latest Technology

Non Contact In-liquid Imaging and Ion Conductance Microscopy
XE-Bio is a powerful 3-in-1 nanoscience research tool that uniquely combines industry’s only True Non-Contact AFM with Ion Conductance Microscopy (ICM) and inverted optical microscope on the same platform. The modular design of the XE-Bio allows easy exchange between non-contact AFM and ICM. Designed for non-invasive in-liquid imaging, the combined imaging capability of AFM, ICM, and inverted optical microscopy makes the XE-Bio ideal for imaging biological samples, such as living cells, in dynamic conditions. Moreover, ICM can be adapted to enable a host of powerful applications in nanoscale electrophysiology.
Powerful 3-in-1 Nanoscale Research Tool with Modular Platform

-> True Non-Contact Atomic Force Microscope (AFM)

->Ion Conductance Microscope (ICM)

-> Inverted Optical Microscope

Ultimate AFM Resolution by True Non-Contact ModeTM

-> 10 times larger Z-scan bandwidth than a piezotube

-> Less tip wear for prolonged high-quality and high-resolution imaging

-> Minimized sample damage or modification

-> Immunity from parameter-dependent results observed in tapping imaging

-> Single molecule Force-Distance spectroscopy with automated data analysis

Non-invasive In-liquid Imaging by ICM

-> Monitoring ion channels of single living cells

-> Unique functional capability of targeted localized stimulation

-> Enable nanoscale patch-clamping for electrophysiology

-> Environmental chamber for temperature, pH, and humidity control

Fully Integrated Inverted Optical Microscope

-> Compatible with phase contrast and DIC imaging

-> Also compatible with fluorescence microscopy

-> Advanced image overlay functions